Christian Bale as Melvin Purvis
Johnny Depp as John Dillinger
Channing Tatum as Pretty Boy Floyd
Billy Crudup as J. Edgar Hoover
Leelee Sobieski as Polly Hamilton
Emilie de Ravin as Anna Patzke
Giovanni Ribisi as Alvin Karpis
David Wenham as Pete Pierpont
Marion Cotillard as Billie Frechette
Stephen Dorff as Homer Van Meter
Stephen Graham as Baby Face Nelson
Rory Cochrane as Carter Baum
Lili Taylor as Sheriff Lillian Holley
Stephen Lang as Charles Winstead
John Ortiz as Phil D'Andrea
Shawn Hatosy as John Madala
Joe DeVito as Guard / Prisoner in Chain Gang
James Russo as Walter Dietrich
Carey Mulligan as Carole
Matt Craven as Gerry Campbell
Luce Rains as Edwin Norris
Branka Katic as Anna Sage
Spencer Garrett as Tommy Carroll
J as on Clarke
Suzy Brack as Biograph Theater Couple
Angelina Lyubomirova as Coat Check Girl
Michael Vieau as Ed Shouse
Peter Gerety as Louis Piquett
Christian Stolte as Charles Makley
Tommy Bartlett as Gold Co
Tracey Ruggiero as Red's hostage
Jennifer Badger as Red's Hostage
Emily Margaret Heitzer as Billie's Girlfriend
Rebecca Spence as Doris Rogers
Suzanne Prescott as Dillinger's Hostage
Alan Wilder as Robert Estill
Joseph Luis Caballero as FBI Agent
Don Frye as Clarence Hurt
John Michael Bolger as Martin Zarkovich
Richard Short as Sam Cowley
Brian Connelly as Office Chester Boyard
Michael Bentt as Herbert Youngblood
Chandler Williams as Clyde Tolson
Don Kress as Convict
Nancy McCrumb as Tommy Carroll's Hostage
Geoffrey Cantor as Henry Suydam
Holly Barrett as Pierpont's Hostage
Bill Camp as Frank Nitti
Carlos Villalobos as FBI Agent
Claire Tuft as Billie's Neighbor
Marc Grapey as Charlie Shapiro
Joseph Mazurk as Guard Bryant
Adam Mucci as Harold Reinecke
Jordan Lawson as Prisoner
John Hoogenakker as Hugh Clegg
Guy Van Swearingen as Agent Brown
Randy Ryan as Julius Rice
Kurt Naebig as William A. Rorer
Madison Dirks as Warren Barton
John Thurner as Homeless Man
Turk Muller as Chicago P.D. Detective
Jonathan M